Lamprey endocrinology is not ancestral

endocrinology is fascinating

Endocrinology Is Fascinating

Endocrinology defined earlier as the study of cell communication via messenger molecules or hormones transversing extracellular space, now extends to inter and intra cellular spaces. Development of the understanding of functioning of endocrine glands parallels the evolution of clinical sciences in the history of medicine. For example Rhazes, died 925 A.D, discussed in detail the sex organs and ...

P-value: What is and what is not

The misinterpretation and misuse of p-value have been increasing for decades. In March 2016, the American Statistical Association released a statement to warn about the use and interpretation of p-value. In this study, we provided a definition and discussion of p-value and emphasized the importance of its accurate interpretation.    

Chronic fatigue: is it endocrinology?

Fatigue and stress-related illnesses often become diagnoses of exclusion after extensive investigation. 'Tired all the time' is a frequent reason for referral to the endocrine clinic, the implicit question being--is there a subtle endocrine pathology contributing to the patient's symptoms? Often initial assessment suggests not but there are no clear data to address the question of whether overt...

Ancestral network module regulating prdm1 expression in the lamprey neural plate border.

prdm1 is an important transcriptional regulator that plays diverse roles during development of a wide variety of vertebrate and invertebrate species. prdm1 is required for neural crest specification in zebrafish, but not in mouse embryos. The role of this gene in neural crest formation in other species has not been examined, and its regulation during embryonic development is poorly understood. ...